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  • 1
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 141 (1973), S. 293-305 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The gular gland of the bat Tadarida brasiliensis is a specialized sebaceous gland located in the skin of the suprasternal region of adult males. It consists of an aggregation of simple branched tubulo-acinar gland units, the number of which varies seasonally. Each acinus is composed of densely packed sebaceous cells at various stages of differentiation. Acinar basal cells and cells of the epithelium of the ducts can differentiate into sebaceous cells. Two main changes appear in the cytoplasm concurrent with the sebaceous transformation: the differentiation of cytoplasmic organelles and the deposition of lipid material. The appearance of a different type of mitochondrion and the development of large numbers of ribosomes and polyribosomes can be recognized in the cytoplasm at an early stage of differentiation. Concomitant with the deposition of significant numbers of lipid droplets, the cells develop abundant agranular endoplasmic reticulum occurring mainly as scattered tubular cisternae. These at times form whorls surrounding lipid droplets. At later stages, the cisternae of the agranular endoplasmic reticulum often occur in crystalline arrays between secretory oil droplets. The roles of the different cytoplasmic organelles, especially in relation to the production of sebum, are discussed.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The development of the human renal glomerulus, in particular its filtering membrane, has been studied by light microscopy with a high resolution technique as a necessary and complementary step for electron microscopical studies.The glomerular filtering membrane is a triple layered structure composed of the visceral epithelium, the capillary endothelium and a basement membrane interposed between them. These three layers have different and definite origins in the metanephrogenic blastema, but close interdependency during the developmental process exists. Mesenchymal cells were demonstrated migrating from the renal interstitium into the invaginating wall of the renal vesicle and transforming into the endothelial and mesangial cells. The visceral epithelium originates from the invaginated wall of the primitive renal vesicle and is transformed from a mass of cells into a special membrane concomitant with the differentiation of the capillary loops. The basement membrane is produced later by the close association of the other two cellular layers.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 146 (1976), S. 449-453 
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The use of tannic acid to preserve and promote the staining of protein constitutents of the extracellular fluid is described. Its usefulness for delineating the extracellular compartment and detecting changes in capillary permeability is illustrated in experiments on the testis.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The fine structure of testicular interstitial cells from mice submitted to different experimental conditions is described. Following treatment with methallibure (I.C.I. 33,828; 1-α-methylallylthiocarbamoyl-2-methylthiocarbamoylhydrazine), a selective inhibitor of hypophyseal gonadotropic activity, interstitial cells acquire a quiescent appearance characterized by: (1) accentuated segregation of agranular endoplasmic reticulum from other cytoplasmic organelles and inclusions, (2) increased depots of lipid droplets. A single injection of interstitial-cell-stimulating hormone (ICSH or LH) induces prominent changes in the ultrastructure and distribution of cell inclusions and organelles that are seemingly related to augmented secretory activity. The cell surface shows a striking development of cytoplasmic processes that interdigitate with similar processes from adjacent cells. Intercellular spaces form a system of interfacial channels providing a direct connection of the interstitial cell surface with blood vessels and the myoid layer of seminiferous tubules. Gonadotropic stimulation causes an increased number of free ribosomes and expansion of the Golgi complex and rough endoplasmic reticulum. There is a marked depletion of lipid droplets and formation of lipofuscin granules.
    Type of Medium: Electronic Resource
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