ISSN:
0003-276X
Keywords:
Life and Medical Sciences
;
Cell & Developmental Biology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
Notes:
Actively growing rats and rabbits received a single intraperitoneal injection of radioactive calcium (2.5 - 10 μc/100 gm) or alizarin red (50 - 100 mg/kg). Contact autoradiographs and gross, macerated dry alizarin specimens were prepared. In addition some alizarin specimens were sectioned serially, without prior decalcification, and the results of the various techniques were compared to determine if morphologic appearance were in agreement.Many similarities were found in corresponding regions of the radioactive calcium and alizarin preparations which included the tibia, cartilaginous joints of the skull base, the bones of the vault, the olfactory fossa, tympanic bulla and the malar process of the maxilla. In every instance the findings were in agreement, particularly in relation to the pattern of deposition and resorption in the growth of these regions, and the results were confirmed by reference to histologic control material.It was concluded that radioactive calcium and alizarin red are deposited similarly in growing bones, including those of the skull, and the results which can be obtained by the use of the two substances are fully complementary.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/ar.1091450113
Permalink
