ISSN:
1432-0428
Keywords:
Pancreas transplantation
;
Glycaemic indices
;
Plasma C-Peptide
;
Lipids
;
Lipoproteins
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary We report the long-term metabolic observations made on 37 patients after simultaneous pancreas and kidney transplantation. Plasma C-peptide levels were above the physiological range in all patients and there was no significant difference between patients undergoing delayed duct occlusion (n=12) or those with drainage of exocrine secretion into the urinary bladder (n=25). HbA1c was equally at the upper end of the normal range in both subsets of patients. Mean fasting cholesterol (237 mg/dl) and triglycerides (122 mg/dl) were normal, and HDL-cholesterol was above normal with an average concentration of 77 mg/dl. Two patients underwent an oral fat tolerance test and showed extremely low postprandial lipaemia and very high lipoprotein lipase activities. We conclude that patients with a functioning pancreas graft persistently demonstrate normoglycaemia, elevated C-peptide, and a very favourable lipid profile both in the fasting and the postprandial state.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00587618
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