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  • Long-term mean blood glucose concentration  (1)
  • Type 1 diabetes  (1)
  • insulin dependent diabetes  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Variation in125i-insulin absorption and blood glucose concentration (1979)
    Springer
    Diabetologia 17 (1979), S. 291-295 
    Details
    ISSN: 1432-0428
    Keywords: Insulin absorption ; intermediate acting insulin ; reactive hyperglycaemia ; Somogyi effect ; insulin dependent diabetes ; insulin therapy ; 125I-insulin ; Monotard insulin ; Isophane insulin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The absorption of monocomponent porcine125I-insulin Monotard and Isophane was studied in six insulin dependent diabetic patients over a period of 12 days. The absorption of insulin was measured as the disappearance of radioactivity from sites of injection. The daily125I-insulin doses ranged from 20 to 48 IU between patients. The insulin absorbed varied considerably within and between patients. The range of individual daily absorbed insulin varied from 19 to 104 per cent of the125I-insulin dose. A significant correlation (p〈0.05) was found between insulin absorption and blood glucose concentration. Insulin absorption rates were relatively high before all hypoglycaemic episodes and reactive hyperglycaemia was only observed when relatively low insulin absorption rates followed the hypoglycaemic attack. The results show that lability in some insulin dependent diabetics is explained by variation in insulin absorption.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01235885
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Glycosylated haemoglobin and steady-state mean blood glucose concentration in type 1 (insulin-dependent) diabetes (1982)
    Springer
    Diabetologia 23 (1982), S. 403-405 
    Details
    ISSN: 1432-0428
    Keywords: Long-term mean blood glucose concentration ; glycaemic control ; haemoglobin A1c ; Type 1 diabetes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Since glucose control and glycosylated haemoglobin varies asyncroneously, we have studied the steady-state relationship between these two factors. In Type 1 (insulin-dependent) diabetic patients with a constant haemoglobin A1c during the preceding 2 years, 15 ambulatory blood glucose profiles during a 5-week period showed a constant glucose level and provided a precise estimate of the mean blood glucose concentration. In addition, we studied 15 non-diabetic subjects who provided three glucose profiles and had one haemoglobin A1c determination performed. A good correlation was found for a curvilinear relationship (haemoglobin A1c=2.07 x mean blood glucose0.596, r=0.98). This close relationship indicates that glycosylated haemoglobin is a valuable, but not very sensitive, index of glucose control.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00260951
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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