ISSN:
1573-4986
Keywords:
unsaturated disaccharide
;
glycosaminoglycan
;
heparin
;
heparan sulfate
;
FABMS
;
CID
;
MS/MS
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract Negative-ion fast atom bombardment tandem mass spectrometry has been used in the characterization of non-, mono-, di- and trisulfated disaccharides from heparin and heparan sulfate. The positional isomers of the sulfate group of monosulfated disaccharides were distinguished from each other by negative-ion fast atom bombardment tandem mass spectra, which provide an easy way of identifying the positional isomers. This fast atom bombardment collision induced dissociation mass spectrometry/mass spectrometry technique was also applied successfully to the characterization of di- and trisulfated disaccharides.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00731361
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