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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 51 (1973), S. 42-44 
    ISSN: 1432-1440
    Keywords: Gastric secretion ; gastrin ; methylxanthines ; Magensekretion ; Gastrin ; Methylxanthine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung An 10 Probanden wurde untersucht, ob Methylxanthine (Theophyllin, Coffein) eine Stimulation der Säuresekretion durch Erhöhung des Serum-Gastrinspiegels hervorrufen. Der Serum-Gastrinspiegel wurde radioimmunologisch vor und nach der intravenösen Infusion von 193,2 mg Theophyllin (Euphyllin) bestimmt. Ein signifikanter Anstieg des Serum-Gastrinspiegels konnte nicht festgestellt werden, obwohl die Säuresekretion bei einer Vergleichsgruppe (n=16) bereits unter der Infusion von 64,5 mg Theophyllin signifikant anstieg.
    Notes: Summary In 10 test subjects it was investigated, whether the mechanism of acid stimulation by methylxanthines (theophylline, caffeine) operates through an elevation of the serum gastrin level. Serum gastrin concentrations were estimated radioimmunologically before and after the i.v. infusion of 193.2 mg theophylline (Euphylline). A significant increase of the serum gastrin level was not observed, although there was a significant rise of the acid output in a control group (n=16) with the i.v. infusion of 64.5 mg theophylline only.
    Type of Medium: Electronic Resource
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