ISSN:
0263-6484
Keywords:
Neurology
;
nerve growth factor
;
NGF-Sepharose
;
NGF-receptor
;
sensory neurones
;
receptor
;
Chemistry
;
Biochemistry and Biotechnology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Biology
,
Medicine
Notes:
Dispersed sensory ganglion cells from the embryonic chick, but not cells from other tissues, liberate biologically active material from nerve growth factor coupled to Sepharose beads. Experiments with such insolubilized material cannot then be taken as evidence for the existence of an external membrane receptor for the factor and may indicate that responsive cells have the ability to cleave an active fragment from the polypeptide.
Additional Material:
2 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cbf.290010207
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