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  • 1
    ISSN: 1432-2072
    Keywords: Key words Sumatriptan ; Food intake ; Plasma growth hormone ; Women
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We studied the effect of the 5-HT1B/1D receptor agonist sumatriptan (6 mg SC) on plasma growth hormone and prolactin and food intake in 15 healthy female subjects using a double-blind, placebo-controlled, cross-over design. Sumatriptan significantly elevated plasma growth hormone but did not alter plasma prolactin. Sumatriptan also significantly lowered total food intake in a buffet meal, particularly decreasing the intake of fat. Our results indicate that 5-HT1B/1D receptors may be involved in the regulation of food intake in humans. In addition, while activation of 5-HT1B/1D receptors stimulates growth hormone release in both men and women, sumatriptan lowers plasma prolactin only in men, suggesting sex differences in the 5-HT regulation of prolactin release.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of thermal analysis and calorimetry 54 (1998), S. 901-911 
    ISSN: 1572-8943
    Keywords: cobalt ; isomorphous substitution ; manganese ; tetraalkylammonium cations
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Pure silica zeolite ZSM-5 has been synthesised in a slightly acidic aqueous fluoride medium which produces the protonated form of the zeolite ZSM-5 [1]. Tetrahalometallate [2] species of cobalt and manganese have been synthesised and increasing mole fractions incorporated into the zeolite synthesis gel. The products have been analysed and characterised using simultaneous thermogravimetric-derivative thermogravimetric analysis (TG-DTG). The thermal decomposition, under nitrogen of the associated tetraethylammonium (TEA+) and tetrapropylammonium (TPA+) cations occluded within the zeolite channels is indicative and characteristic of the incorporation of the heteroatoms into the zeolitic framework. Analysis by X-ray diffraction (XRD), scanning electron microscopy (SEM), X-ray fluorescence (XRF), and Fourier transform infrared spectroscopy (FTIR) has confirmed the reliability of thermogravimetric (TG) and derived thermogravimetric analysis (DTG) as a diagnostic tool.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of thermal analysis and calorimetry 63 (2000), S. 329-338 
    ISSN: 1572-8943
    Keywords: copper ; fluoride ; isomorphous substitution ; nickel ; ZSM
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The synthesis of pure silica ZSM-5 has been modified to produce highly crystalline material in the protonated form, necessary for catalytic activity, directly from a low water fluoride gel. Tetrahedrally co-ordinated divalent species of nickel and copper have been synthesised as salts of large organic cations and increasing mole fractions incorporated into the zeolite gels. The products have been analysed and characterised using simultaneous thermogravimetric and derivative thermogravimetric analysis (TG-DTG). The thermal decomposition under nitrogen of the metal associated cations, tetraethylammonium (TEA+), occluded within the zeolite channels is indicative and characteristic of the incorporation of heteroatoms into the zeolite framework. Anomalous losses in the systems can be explained by Jahn–Teller distortions. The mass losses increased with increased metal loading and were consistent with those reported in full water system, analysis also confirmed that the material was hydrophobic and thermally stable. Analysis by X-ray diffraction (XRD), scanning electron microscope (SEM), X-ray fluorescence (XRF), Fourier transform infrared spectroscopy (FTIR) and Atomic Absorption Spectroscopy (AAS) has confirmed the reliability of TG-DTG as a diagnostic tool. The maximum levels of substitution achieved were (mass%) Ni 3.93 and Cu 4.38.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1439-6327
    Keywords: Key words Carbohydrate ; Dehydration ; Metabolism ; Recovery ; Thermoregulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Recovery from prolonged exercise involves both rehydration and replenishment of endogenous carbohydrate stores. This study examined the influence of drinking a carbohydrate-electrolyte solution on short-term recovery and subsequent exercise capacity in a warm environment. Thirteen healthy male volunteers completed two trials, at least 7 days apart. On each occasion subjects performed an initial treadmill run at 60% of maximal oxygen uptake (VO2max), for 90 min or until volitional fatigue (T1), in a warm environment (35 °C, 40% relative humidity, RH). Volitional ingestion of water was permitted during each of the exercise trials. During a subsequent 4-h recovery period (REC) subjects consumed either a 6.9% carbohydrate-electrolyte solution (CES) or a sweetened placebo (P), in a volume equivalent to 140% of body mass loss. Following REC, subjects ran to exhaustion at the same %VO2max in order to assess their endurance capacity (T2). Mean (SEM) run times during T1 did not differ between the CES [74.8 (4.6) min] and P [72.5 (5.2) min] trials. Body mass was reduced (P 〈 0.01) by 1.9 (0.2)% (CES) and 1.7 (0.2)% (P), and plasma volume (P 〈 0.01) by 6.0 (0.9)% (CES) and 5.4 (1.0)% (P) during the T1 trials. During REC 2006 (176) ml and 1830 (165) ml of fluid was ingested, providing 138 (12) g and 0 g of carbohydrate in the CES and P trials, respectively. Prior to T2, plasma volume and net fluid balance were similarly restored [CES +58 (26) g; P −4 (68) g] in both trials. During T2 the exercise duration was longer (P 〈 0.01) in the CES compared to the P trial [CES 60.9 (5.5) min; P 44.9 (3.0) min]. Thus, provided that an adequate hydration status is maintained, inclusion of carbohydrate within an oral rehydration solution will delay the onset of fatigue during a subsequent bout of prolonged submaximal running in a warm environment.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 39 (1978), S. 7-16 
    ISSN: 1439-6327
    Keywords: Exercise ; Carbohydrate ; Metabolism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Four subjects were studied during exercise at 50% of maximum oxygen uptake after a normal diet, after a low carbohydrate (CHO) diet following exercise-induced glycogen depletion, and after a high CHO diet. This regime has previously been shown to cause changes in the amount of glycogen stored in the exercising muscles. Metabolic and respiratory parameters were measured during the exercise. The respiratory exchange ratio, blood lactate, blood pyruvate, blood glucose and plasma triglycerides were lower than normal following the low CHO diet and higher than normal following the high CHO diet. Plasma free fatty acids and plasma glycerol were higher than normal after the low CHO diet and lower than normal after the high CHO diet. The contribution of CHO to metabolism was less than normal after the low CHO diet and greater than normal after the high CHO diet. The altered availability of FFA does not appear to be a result of the variations in the blood lactate content.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 50 (1982), S. 133-144 
    ISSN: 1439-6327
    Keywords: Fatigue ; Oxygen uptake ; Isometric and rhythmic exercise ; Women ; Lifting exercise
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Physiological responses were measured in 7 women subjects who lifted boxes weighing 6.8, 15.9 or 22.7 kg from the floor to a height of 60 cm. After training and establishing the $$\dot V$$ O2 max, the boxes were lifted for 1 h at 30, 50, and 60% $$\dot V$$ O2 max. The changes in heart rate, $$\dot V$$ O2, the integrated EMG during lifting and the loss of isometric hand-grip endurance after lifting were used to assess the development of fatigue. There was no evidence of fatigue at 30% $$\dot V$$ O2 max but fatigue did exist in some conditions at 50% and in all conditions at 60% $$\dot V$$ O2 max. It is suggested that fatigue is unlikely to occur while lifting boxes up to 15.9 kg weight at 35–40% $$\dot V$$ O2 max, i.e., at rates of lifting varying from 5 to 7 times per min.
    Type of Medium: Electronic Resource
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