ISSN:
1432-1335
Keywords:
Biotransformation
;
Carcinogens
;
Heterogeneity
;
liver cells
;
Fluoranthene
;
Microfluorescence
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Pathways of biotransformation of the carcinogenic polycyclic hydrocarbon fluoranthene in individual isolated perifused liver cells were delineated using noninvasive microfluorescence spectroscopic techniques. An example of heterogeneity of coupling between phase I and phase II enzymes detected in a population of β-naphthoflavone-induced rat liver cells demonstrates the usefulness of the experimental model of perifused liver cells.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00390484
Permalink