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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 101 (1990), S. 66-71 
    ISSN: 1432-2072
    Keywords: Opioids ; Saline intake ; Naloxone ; Reward ; Palatability ; Taste preference ; Drinking
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Endogenous opioid peptides are thought to play a role in mediating the palatability or rewarding aspects of sweet tastes. There is also evidence, however, which suggests that opioids may influence the preference for the taste of salt as well. In the present studies, we measured the effects of central administration of naloxone and the mu agonist [d-Ala2,MePhe4,Gly-ol5]enkephalin (DAGO) on the ingestion of salt solutions. In non-deprived rats given a choice of water and 0.6% saline, ICV injections of DAGO (1 and 3 nmol) significantly increased the intake of 0.6% saline; baseline water intake was minimal and was unaffected by DAGO. When rats were given a choice between water and 1.7% saline, DAGO stimulated both water and saline intake. Because 1.7% saline is a hypertonic solution, the increase in water intake may have been secondary to saline intake. In rats on a deprivation schedule in which water and 0.6% saline were available for only 2–3 h/day, there was a tendency for DAGO to increase 0.6% saline intake and decrease water intake, though these effects were not significant. In rats given water and 1.7% saline, DAGO increased saline intake and had no effect on water intake. Naloxone was also tested in water-deprived rats. Naloxone (20 and 50 µg) significantly decreased 0.6% saline intake; baseline water intake was low (3–5 ml) and was unaffected by naloxone. When rats were given a choice between water and 1.7% saline, naloxone (50 µg) significantly reduced water intake, while intake of 1.7% saline was slightly increased. These results suggest a role for central mu opioid receptors in mediating the preference for salt solutions.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International journal of computer vision 44 (2001), S. 111-135 
    ISSN: 1573-1405
    Keywords: vision ; object location ; Monte Carlo ; filter-bank ; statistical independence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract A Bayesian approach to intensity-based object localisation is presented that employs a learned probabilistic model of image filter-bank output, applied via Monte Carlo methods, to escape the inefficiency of exhaustive search. An adequate probabilistic account of image data requires intensities both in the foreground (i.e. over the object), and in the background, to be modelled. Some previous approaches to object localisation by Monte Carlo methods have used models which, we claim, do not fully address the issue of the statistical independence of image intensities. It is addressed here by applying to each image a bank of filters whose outputs are approximately statistically independent. Distributions of the responses of individual filters, over foreground and background, are learned from training data. These distributions are then used to define a joint distribution for the output of the filter bank, conditioned on object configuration, and this serves as an observation likelihood for use in probabilistic inference about localisation. The effectiveness of probabilistic object localisation in image clutter, using Bayesian Localisation, is illustrated. Because it is a Monte Carlo method, it produces not simply a single estimate of object configuration, but an entire sample from the posterior distribution for the configuration. This makes sequential inference of configuration possible. Two examples are illustrated here: coarse to fine scale inference, and propagation of configuration estimates over time, in image sequences.
    Type of Medium: Electronic Resource
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