Electronic Resource
Springer
Journal of molecular medicine
61 (1983), S. 251-253
ISSN:
1432-1440
Keywords:
Motilin
;
IDMC
;
Gallstone disease
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Plasma motilin concentrations were measured in eight controls and 11 patients with radiolucent gallstones over a period of 3–4 h following an overnight fast. In five of these patients the interdigestive motor complex (IDMC) was studied simultaneously. The results indicate: a) cyclical changes of plasma motilin concentrations (mean cycle duration 110±9.9 and 102±8.4 min, $$\bar x$$ ±SEM) and a significant correlation between the basal intercyclical motilin concentrations and the age (p〈0.02) in the controls and the gallstone patients studied, and b) a significant correlation between the maximal motilin increase and the age in the controls (p〈0.01) but not in the gallstone patients. The results therefore suggest a different behaviour of the interdigestive motilin patterns in controls and gallstone patients. As the motilin cycles were accompanied in 90% with an IDMC in the five patients studied this conclusion might include an abnormal interdigestive motor activity within the intestinal tract in gallstone patients.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01496131
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