ISSN:
0192-253X
Keywords:
Mu1
;
Mutator
;
Maize alcohol dehydrogenase
;
Transposable elements
;
Gene expression
;
Processing
;
Life and Medical Sciences
;
Genetics
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Biology
Notes:
We have examined effects of mutations created by transposition of the Mu1 element of maize into genes coding for Adh1 and Sh1, by means of allozyme measurements, DNA and RNA hybridization, cloning, and sequencing. From our analysis of mutant alleles we conclude that the element acts both to reduce steady-state levels of RNA and to induce aberrant processing of primary transcripts. We also conclude that genetic background can exert considerable influence in determining the degree to which Mu affects these aspects of gene expression.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/dvg.1020100606
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