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  • 1
    Electronic Resource
    Electronic Resource
    Filamentous and multilamellated cytoplasmic inclusions in progressive multifocal leukoencephalopathy (1977)
    Springer
    Acta neuropathologica 37 (1977), S. 263-265 
    Details
    ISSN: 1432-0533
    Keywords: Progressive multifocal leukoencephalopathy ; Multiple sclerosis ; Demyelination ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Inclusions identical to those described in multiple sclerosis (MS) brain by Prineas (1975) have been seen by ultrastructural study of cerebral tissue in two elsewhere reported cases of Progressive Multifocal Leukoencephalopathy (PML). The meaning of these formations, which have been suggested to be related to a special process of demyelination in MS, is discussed in the light of the hypotheses concerning the demyelination mechanism in PML. Whatever might be their significance, these cytoplasmic non viral inclusions are not specific for MS.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00686889
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Immunofluorescence studies of intra cytoplasmic immunoglobulin binding lymphoid cells (CILC) in the central nervous system. Report of 32 cases including 19 multiple sclerosis (1977)
    Springer
    Acta neuropathologica 40 (1977), S. 227-232 
    Details
    ISSN: 1432-0533
    Keywords: Demyelinative diseases ; Lymphoid cells ; B cells ; Multiple sclerosis ; Subacute sclerosing panencephalitis ; Progressive multifocal leukoencephalopathy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In 32 cases of human neurological disorders, including 19 cases of Multiple Sclerosis, an analysis was performed on formalin fixed paraffin embedded brain tissue, by using fluorescein labelled antibodies and Nomarski optics. This method, which allows the reduction of technical artifarcts, permitted to establish the presence of intracytoplasmic immunoglobulin binding lymphoid cells with IgG and IgA, more rarely IgM, in the majority of the multiple sclerosis cases. This supports the theory of the intrathecal secretion of antibodies within the central nervous system but does not allow to explain the function of those B. Lymphocytes. The same immunological picture was found in Subacute Sclerosing Panencephalitis. On the contrary, it was different in Progressive Multifocal Leucoencephalopathy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691958
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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