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  • Polymer and Materials Science  (4)
  • Myelomonocytic leukemia cell  (2)
  • Positron emission tomography  (2)
  • 1
    ISSN: 0005-2728
    Keywords: (Murine) ; Differentiation ; Histamine ; Histidine decarboxylase ; Macrophages ; Myelomonocytic leukemia cell ; [abr] HDC ; [abr] L-histidine decarboxylase (L-histidine carboxy-lyase, EC 4.1.1.22) ; [abr] post-endotoxin serum, the serum which was obtained from mice
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0167-4889
    Keywords: (Murine) ; Differentiation ; Histamine ; Histidine decarboxylase ; Macrophages ; Myelomonocytic leukemia cell
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1920
    Keywords: Mitochondrial encephalomyopathy ; Cerebral oxygen metabolism ; Cerebral glucose metabolism ; Cerebral blood blow ; Positron emission tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Cerebral blood flow (CBF), oxygen metabolism (CMRO2), and glucose metabolism (CMRGlc) were measure using positron emission tomography in five patients diagnosed as having mitochondrial encephalomyopathy. The molar ratio between the oxygen and glucose consumptions was reduced diffusely, as CMRO2 was markedly decreased and CMRGlc was slightly reduced. The CBF showed less changes. The CBF increase on hypercapnia was smaller than normal, though this was not significant. CBF with hypocapnia demonstrated a significant reduction compared with the normal. These results suggest that oxidative metabolism is imparied and anaerobic glycolysis relatively stimulated, due to a primary defect of mitochondrial function, and that mild lactic acidosis occurs in brain tissue because of impaired utilisation of pyruvate in the TCA cycle. As these findings appear to indicate directly a characteristic of this disease, such measurements may be a useful tool for assessment of the pathophysiology and for diagnosis of mitochondrial encephalomyopathy.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1920
    Keywords: Key words Mitochondrial encephalomyopathy ; Cerebral oxygen metabolism ; Cerebral glucose metabolism ; Cerebral blood blow ; Positron emission tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Cerebral blood flow (CBF), oxygen metabolism (CMRO2), and glucose metabolism (CMRGlc) were measured using positron emission tomography in five patients diagnosed as having mitochondrial encephalomyopathy. The molar ratio between the oxygen and glucose consumptions was reduced diffusely, as CMRO2 was markedly decreased and CMRGlc was slightly reduced. The CBF showed less changes. The CBF increase on hypercapnia was smaller than normal, though this was not significant. CBF with hypocapnia demonstrated a significant reduction compared with the normal. These results suggest that oxidative metabolism is impaired and anaerobic glycolysis relatively stimulated, due to a primary defect of mitochondrial function, and that mild lactic acidosis occurs in brain tissue because of impaired utilisation of pyruvate in the TCA cycle. As these findings appear to indicate directly a characteristic of this disease, such measurements may be a useful tool for assessment of the pathophysiology and for diagnosis of mitochondrial encephalomyopathy.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 17 (1983), S. 679-690 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Particles of a lithium aluminum silicate, which had been treated with a silane coupling agent, were centrifuged either in an adduct of bisphenol-A/glycidyl methacrylate (Bis-GMA) or in a mixture of Bis-GMA and methyl methacrylate. Polymerization was effected by heating with 2,5-dimethyl-hexane-2,5-dihydroperoxide. Flexural strength passed through an optimum value with increasing loading of the silicate. Inclusion of 4-methacryloxyethyl trimellitic anhydride, 4-META (5 wt % on monomer), increased the optimum flexural strength by about 20% (to 240 MPa). Evidence that 4-META increased the adhesion of filler particles to the polymeric matrix was obtained by examination of fracture surfaces.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 18 (1984), S. 1089-1103 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: The main objective was to evaluate the use of 4-methacryloxyethyl trimellitate anhydride (4-META) to improve bonding of composite materials to dentin. Bowen's resin, containing camphoroquinone, was polymerized by exposure to visible light. In composites, made with a silanated silicate, inclusion of 4-META (3%) had little effect in increasing mechanical strength or adhesion to bovine teeth. However, direct application of 4-META via acetone solution was found to be an effective way of increasing tensile adhesive strength; by 240% to dentin (to 7.2 MPa) and by 160% to enamel (to 10.8 MPa). Applying the experience mentioned above, 4-META was used to bond a proprietary photocuring microfilled composite material to Class V cavities in freshly extracted human teeth. After thermal cycling between water baths held at 5°C and 60°C, all dentin restorations without 4-META failed, as judged by marginal leakage of a dyestuff. In contrast, using 4-META there was no leakage in 9 out of 10 cases. In restorations involving enamel, 4-META failed to prevent marginal leakage at the enamel margins but did prevent penetration along the dentin/composite interface. It is concluded that 4-META shows great promise for preventing marginal leakage at dentin/composite interfaces.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 19 (1985), S. 631-642 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Pastes were made by spatulating a hydroxyapatite powder into triethylene glycol dimethacrylate (TEGDMA) that contained benzoyl peroxide. For comparison, similar pastes included 5 wt-% 4-methacryloxyethyl trimellitic anhydride (4-META) in the TEGDMA. Composites were made by heating at 120°C under pressure. Inclusion of 4-META reduced the rate of diffusion of water by about one-third, at 27°C. Also after thermal cycling in water, inclusion of 4-META decreased the fractional drop in compressive strength by about one-half. Examination of fracture surfaces indicated that inclusion of 4-META improved the wetting of filler particles and gave more coherent composites. All these findings are consistent with the view that 4-META acts as a coupling agent.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Chemistry Edition 21 (1983), S. 811-818 
    ISSN: 0360-6376
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Methyl methacrylate containing a small amount of 4-methacryloxyethyl trimellitate anhydride (1.0-1.5 wt %) yielded an insoluble network when polymerized in the presence of various inorganic powders, such as lithium aluminum silicate. This unexpected result was obtained for polymerization initiated either by exposure to γ-rays or by heating with azobisisobutyronitrile. In contrast, polymerization in the absence of inorganic powder gave the expected soluble products. Therefore, it is concluded that the inorganic particles play a role in network formation. In order to account for network formation even in a supernatant layer of clear monomer, i.e., above the centrifuged sedimentation volume of the powder, it is suggested that the monomer reacts on the surface of particles to form a diffusive crosslinking agent.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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