ISSN:
1432-0533
Keywords:
Key words Cerebellar myoneurocytoma
;
Neurofilament
;
Synaptophysin
;
Desmin
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract An unusual case of cerebellar neurocytoma with rhabdomyomatous differentiation in a 6-year-old boy is reported. Immunocytochemical and ultrastructural features of the tumour were studied. Abortive synapse formation, the presence of clear vesicles and synaptophysin immunoreactivity of the tumour cells indicated its intermediate neuronal differentiation, while the presence of myoblasts and myotubes and immunolabelling by desmin confirmed the rhabdomyomatous differentiation. In addition, the mesenchymal cells variably expressed neurofilament protein and glial fibrillary acidic protein, suggesting inductive interaction between the neuroectodermal and ectomesenchymal elements and persistence of the pleuripotential nature of the cells along the rhombic area of the brain stem.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s004010050805
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