ISSN:
1432-1076
Keywords:
Key words Tick-borne encephalitis
;
Passive immunization
;
Sequalae
;
Cerebrospinal fluid
;
Neuroimaging
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract We report on a 5-year-old girl with an unusually severe course of tick-borne encephalitis following passive immunization with specific hyperimmune globulin after a tick bite in an endemic area. Serial investigations of the CSF revealed intrathecal production of specific antibodies paralleled by increasing numbers of B-cells after initial T-cell pleocytosis. Focal central lesions were evident on MRI. Conclusion The severity of the presented case questions the benefit of passive immunization and rather justifies consideration of vaccine recommendation to residents and travellers to areas endemic for tick-borne encephalitis virus.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02002905
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