ISSN:
0887-624X
Keywords:
poly(ethylenimine)
;
2-carboxypyrazinyl
;
self-optimization
;
Ni(II) binding
;
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
To test the concept of self-optimization of own binding site by a metal ion, host molecules for Ni(II) ion were built on poly(ethylenimine) (PEI) by using the ethylenediamine portions of PEI and 2-carboxypyrazinyl (CP) group. Two derivatives of PEI containing CP were prepared: one by random acylation of PEI with pyrazine-2,5-dicarboxylic acid mono-(2,5-dioxo-pyrrolidin-1-yl) ester (PC-DP), and the other by acylation of PEI with PC-DP in the presence of Ni(II) ion. Between these two CP derivatives of PEI, Ni(II) binding ability was more than 103 times greater for the latter. Optimization by Ni(II) ion of its own binding site built on the polymer was attributed to the preassemblage of PC-DP and PEI with Ni(II) ion and the subsequent attack at PC-DP by an amino group of PEI located in an optimal position. © 1997 John Wiley & Sons, Inc. J Polym Sci A: Polym Chem 35: 533-537, 1997.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
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