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  • 1
    Electronic Resource
    Electronic Resource
    Sex-linked differences in avoidance learning in the offspring of rats treated with nicotine during pregnancy (1983)
    Springer
    Psychopharmacology 80 (1983), S. 93-95 
    Details
    ISSN: 1432-2072
    Keywords: Nicotine ; Avoidance learning ; Behavioral teratology ; Sex-linked difference ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The offspring of rats treated with nicotine (0.5 mg/kg/day SC) on days 1–20 of gestation, were trained for active avoidance conditioning when 60 days old. Although learning was similar in both control groups of males and females, nicotine exposure during fetal life improved learning in females but reduced it in males, the difference between these two groups being statistically significant from day 17 until the end of the training period (day 25).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00427504
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Nicotine reverses hemorrhagic shock in rats (1991)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 343 (1991), S. 427-430 
    Details
    ISSN: 1432-1912
    Keywords: Hypovolemic shock ; Hemorrhage ; Nicotine ; Resuscitation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cholinergic mechanisms are currently thought to play an essential role in blood pressure homeostasis. Here we show that, in urethane-anaesthetized rats bled to severe hemorrhagic shock, the i. v. administration of nicotine 0.2–50 μg/kg causes a prompt, sustained and dose-dependent improvement in cardiovascular and respiratory functions, the animals' survival rate being significantly higher than that of animals treated with saline. These effects are prevented by bilateral cervical vagotomy and by concurrent local anaesthesia of the carotid bodies, which suggests that stimulation of visceral afferents is the main mechanism of action of nicotine in hemorrhagic shock.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00179049
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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