ISSN:
0170-2041
Keywords:
Furoxans
;
Nitrile oxides
;
Vasodilator activity
;
Antiaggregatory activity
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The synthesis and structure of a trimer 5 of the furoxan system are reported. The probable origin of this derivative is the dimerization of the intermediate 4-phenyl-3-furoxancarbonitrile oxide (4) obtained by decomposition of the corresponding nitrolic acid 3. The title compound shows a high level of activity as vasodilator and inhibitor of platelet aggregation.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.199319930172
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