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  • Organic Chemistry  (2)
  • Schlüsselwörter Computerunterstützte Chirurgie •¶Medizinrobotik • Orthopädie  (1)
  • 1
    ISSN: 0899-0042
    Keywords: chiral thiol derivatisation ; diastereomeric derivative ; reversed phase HPLC ; fluorescence detection ; assay validation ; enantiomer pharmacokinetics ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A specific plasma level assay for the enantiomers of α-lipoic acid is described. It makes use of liquid-liquid extraction, chemical reduction to the dithiol enantiomers, and their precolumn chiral derivatisation with o-phthalaldehyde in the presence of D-phenylalanine. The two diastereomeric derivatives are separated by reversed-phase HPLC with fluorescence detection. The working range of the assay is between 15 ng/ml (lower limit of quantitation) and 1,000 ng/ml for either enantiomer. Chirality 9:32-36, 1997. © 1997 Wiley-Liss, Inc.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1433-0431
    Keywords: Schlüsselwörter Computerunterstützte Chirurgie •¶Medizinrobotik • Orthopädie ; Keywords Computer-assisted surgery •¶Medical robotics • Orthopedics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract In this paper, we present a medical robot system dedicated to support the surgeon during challenging tasks within orthopedic interventions. The main goal of this work is to develop a system as technically simple as the surgical requirements allow to keep its cost and complexity to a minimum. Therefore, we primarily focus on calibrated X-ray imaging for image acquisition, an easy registration procedure and robotic execution using a positioning device with simple parallel kinematics. Examples of different orthopedic interventions using the compact robot system for image-guided orthopedic surgery (CRIGOS) are presented, as well as various modes of execution of the device.
    Notes: Zusammenfassung Im folgenden Beitrag wird das Konzept und die Entwicklung eines Medizinroboters für die orthopädische Chirurgie behandelt, das den Chirurgen bei der Ausführung komplizierter Eingriffe intraoperativ unterstützten soll. Ein Schwerpunkt der Arbeit ist es, das System so einfach und kostengünstig zu realisieren, wie es die Anwendung erlaubt. Daher greifen wir bei der Bildgebung auf das gängige Verfahren der Röntgenbildgebung zurück. Zur robotischen Ausführung verwenden wir ein einfach, parallel aufgebautes Positioniergerät. Abschließend wird der mögliche operative Ablauf bei Verwendung des bildgeführten Kompaktrobotersystems (CRIGOS) anhand verschiedener orthopädischer Eingriffe exemplarisch aufgezeigt und unterschiedliche Ausführungsstrategien vorgestellt.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 282 (1894), S. 85-107 
    ISSN: 0075-4617
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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