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  • Oxidant stress  (1)
  • Vibrotactile resolution  (1)
  • insulin secretion  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Free Radical Biology and Medicine 16 (1994), S. 763-770 
    ISSN: 0891-5849
    Keywords: F"2-isoprostanes ; Free radicals ; Gas chromatography-mass spectrometry ; Glutathione ; Hydroxy-eicosatetraenoic acids (HETES) ; Lipid peroxidation ; Liver ischemia ; Oxidant stress ; Reperfusion injury
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    ISSN: 1432-0428
    Keywords: Plasma glutathione ; insulin secretion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In isolated rat pancreatic islets exogenous glutathione which is not able to penetrate into cells, augmented glucose (11.1 mmol/l)-mediated insulin release. In the presence of a non-stimulatory glucose concentration (2.8 mmol/l) glutathione had no effect. The half-maximal synergistic action of glutathione on insulin secretion was observed at approximately 8.0 μmol/l. This concentration of glutathione is similar to that found in the plasma of non-fasted anaesthetised rats (6.5 μmol/l). Oral ingestion of glucose increased the arterial plasma glutathione in rats. Our data provide for the first time indirect evidence for a modulating effect of plasma glutathione in postprandial glucose-mediated insulin secretion which appears to be located at the extracellular site of islet cells.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 38 (2000), S. 74-79 
    ISSN: 1741-0444
    Keywords: Two-point vibrotactile discrimination ; Vibrotactile resolution ; Vibrotactile excitation ; Tactile excitation ; Tactile parameter optimisation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract Tactile spatial resolution is an important factor in the design of vibrotactile arrays. The two-point discrimination distance is used as a measure of tactile spatial resolution. An experimental study is presented showing the effect of pulse burst stimulus parameters, pulse repetition period and duty cycle on two-point vibrotactile spatial discrimination. An array of piezoceramic vibrators is used to measure two-point spatial discrimination on the index finger. In a group of 14 subjects, the average two-point discrimination distance for a pulse repetition period of 1/25 s is 2.1 mm (SD=1.0), whereas for 1/500 s it is 5.1 mm (SD=0.9). Differences in discrimination distances are statistically significant according to the ANOVA analysis (p〈0.001). Results show that the two-point discrimination distance is better for longer pulse repetition periods. Therefore the pulse repetition period in an excitatory waveform composed of bursts of pulses is important for tactile resolution. No statistically significant differences in discrimination distances are found between bursts of pulses of 50% duty cycle and those of lower duty cycle. The latter result indicates that, by choosing low-duty cycle waveforms for vibrotactile stimulation, the power can be reduced with no loss in two-point discrimination capacity.
    Type of Medium: Electronic Resource
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