ISSN:
1573-4919
Keywords:
heart
;
vascular endothelium
;
vascular smooth muscle
;
confocal microscopy
;
pH
;
calcium
;
sodium
;
voltage probe
;
heart
;
endothelin-1
;
Angiotensin II
;
PAF
;
nucleus
;
mitochondria
;
SR
;
cardiomyopathy
;
cells interaction
;
R-type Ca2+ channel
;
excitation-contraction coupling
;
dystrophic mouse
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
Notes:
Abstract In recent years, fluorescence microscopy imaging has become an important tool for studying cell structure and function. This non invasive technique permits characterization, localisation and qualitative quantification of free ions, messengers, pH, voltage and a pleiad of other molecules constituting living cells. In this paper, we present results using various commercially available fluorescent probes as well as some developed in our laboratory and discuss the advantages and limitations of these probes in confocal microscopy studies of the cardiovascular system.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1006840228104
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