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  • 1
    ISSN: 1573-2568
    Keywords: OXYGEN FREE RADICALS ; LIPID PEROXIDATION ; CERULEIN ; PANCREATITIS ; MELATONIN
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Since oxygen free radicals and lipidperoxidation have been implicated in the pathogenesis ofan early stage of acute pancreatitis, we examinedwhether melatonin, a recently discovered free-radicalscavenger, could attenuate pancreatic injury inSprague-Dawley rats with cerulein-induced pancreatitis.Acute pancreatitis was induced by four intraperitonealinjections of cerulein (50 μg/kg body wt) given at1-hr intervals. Thirty minutes after the lastcerulein injection, the rats were killed and the degreeof pancreatic edema, the level of lipid peroxidation inthe pancreas, and serum amylase activity were increased significantly. Pretreatment with melatonin (10or 50 mg/kg body wt) 30 min before each ceruleininjection resulted in a significant reduction inpancreatic edema and the levels of lipid peroxidation.Serum amylase activity, however, was notsignificantly influenced by either dose of melatonin.Moreover, we found that cerulein administration wasassociated with stomach edema as well as high levels oflipid peroxidation in the stomach and smallintestine, which were also reduced by melatonin.Melatonin's protective effects in cerulein-treated ratspresumably relate to its radical scavenging ability andto other antioxidative processes induced bymelatonin.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of porous materials 3 (1996), S. 151-155 
    ISSN: 1573-4854
    Keywords: zeolite rho ; aging temperature effect ; crystallization kinetics ; crystal size
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract This paper focuses on deciphering the gel aging temperature effect on the crystallization of zeolite rho(RHO). Increased gel aging temperature (from room temperature to 55°C and no aging) caused an increase in induction periods and decreased the crystallization rate during the synthesis of RHO. Other crystalline phases such as chabazite were formed along with increasing aging temperature. The largest crystal size of RHO increased proportionally to aging temperatures up to about 9 μm. These results suggest that aging temperature greatly affected the crystallization, the crystal sizes, the purity and the formed crystalline phases during the synthesis of zeolite rho. This study suggests that most of RHO nuclei are formed during gel aging and their formation is depressed by the increased aging temperatures.
    Type of Medium: Electronic Resource
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