ISSN:
1432-0428
Keywords:
Diabetes mellitus
;
polycythaemia
;
glycosylated haemoglobin
;
diabetic control
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Sixty-five diabetic patients had a total red cell count significantly greater than 65 age and sex matched non-diabetics; (4.93±0.06×106 and 4.50 ±0.05×106 red cells/ul respectively; p〈0.005). In 110 diabetic patients, total red cell count was positively correlated with the proportion of glycosylated haemoglobin (HbA1) (r=0.32, p〈0.001). The correlation was maintained in 60 of these patients with a mean blood glucose 〈15 mmol/l (r=0.33, p 〈0.05), and in 49 non-smoking diabetic patients (r =0.30, p=0.05). It is proposed that the greater proportion of higher oxygen-affinity HbA1 in comparatively uncontrolled diabetics may be inducing sufficient tissue hypoxia to cause the demonstrated relative polycythaemia.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00251917
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