ISSN:
1432-2013
Keywords:
Renal denervation
;
Sodium excretion
;
Para-aminohippuric acid secretion
;
TmPAH
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Renal excretion of para-aminohippuric acid (PAH) was studied during PAH loading on unilaterally splanchnicotomized (“denervated”) anaesthetized dogs. Urine flow, sodium excretion of denervated kidneys were significantly increased. Below a plasma concentration of 20 mg% there were no differences between intact and denervated kidneys in urinary excretion and in calculated tubular transport of PAH. However, maximum secretion rate on the splanchnicotomized side was significantly decreased (innervated: 34.8, denervated: 25.2 mg/100 ml GFR, respectively). Although both Na reabsorption and PAH secretion are impaired by denervation, the exact mechanism of action of renal sympathectomy is not elucidated as yet.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00581368
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