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  • Persistence  (1)
  • regioselective alkylation  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Mechanisms structuring stream fish assemblages: Are there lessons from introduced species? (1991)
    Springer
    Environmental biology of fishes 30 (1991), S. 359-368 
    Details
    ISSN: 1573-5133
    Keywords: Exotics ; Community ; Persistence ; Competition ; Predation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Synopsis Stream fish faunas are being increasingly subjected to non-native fishes. Successful establishment of non-native forms varies widely between geographic regions (38–77%), but is generally greater in areas that are either altered by man or initially depauperate in fish species. While such introductions have generally had undesirable effects on native fish species, they show no signs of decreasing. Thus, this essay is an attempt to determine if the introduction of non-native fishes may provide insights into processes structuring stream fish assemblages. There are, unfortunately, few detailed ecological studies documenting the response of stream fish assemblages to introduced fishes. Of the 31 studies included in my analysis, the majority (77%) documents a decline in native fishes following the introduction of exotic or transplanted forms. Only 10 studies examined shifts in resource use, of which 5 documented or suggested shifts in habitat. Overall, the responses of native stream fish assemblages to non-native fishes suggest that biotic interactions are important in structuring the impacted assemblages, being implicated in 62% of the studies. Proposed or demonstrated mechanisms are divided equally between competition and predation. Unfortunately, pre-disturbance data are generally lacking so that processes important in structuring native fish assemblages cannot be determined.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02027979
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Regioselective alkylation at the N4 positionof a 3-oxo-1,4-benzodiazepine on solid support (2000)
    Springer
    Molecular diversity 5 (2000), S. 1-5 
    Details
    ISSN: 1573-501X
    Keywords: benzodiazepine ; combinatorial array ; diversity ; Heck reaction ; regioselective alkylation ; Sasrin®
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract An efficient solid phase regioselective alkylation at the N4 positionof a 3-oxo-1,4-benzodiazepine template exemplified by 4-H-2,3,4,5-tetrahydro-7-iodo-3-oxo-1H-1,4-benzodiazepine-2-acetate-polymerester is described. Further chemical elaboration atposition 7, utilizing a modified Heck reaction, allows the incorporationof amides from primary or secondary amines. The two diversity points atpositions 4 and 7 were utilized tosynthesize a 28-membered, combinatorial array on Sasrin® resin in moderate yields and 〉80% purity. Having validated the chemistry on solid support, acombine and splitapproach to prepare a bead-bound combinatorial library is achievableutilizing similar experimental practices and procedures as in thearray synthesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1011377008730
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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