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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 159 (1975), S. 303-309 
    ISSN: 1432-0878
    Keywords: Pinealocytes ; Vacuole ; Hedgehog ; Mole
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Résumé Des cellules particulières de la glande pinéale du Hérisson et de la Taupe, caractérisées par la présence d'une vacuole énorme, ont été étudiées. La présence dans le cytoplasme de ces cellules de grains de sécrétion (chez le Hérisson) et de structures paracristallines (chez la Taupe) permet d'identifier ces cellules comme étant des pinéalocytes. La nature et le rôle de ce phénomène de vacuolisation sont discutés.
    Notes: Summary Special cells in the hedgehog and mole pineal gland which are characterized by an enormous single vacuole were studied. The presence of secretory granules (in the hedgehog) and of paracrystalline structures (in the mole) in the cytoplasm of these cells indicates that they are pinealocytes. The nature and the role of the phenomenon of vacuolization are discussed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 174 (1976), S. 1-24 
    ISSN: 1432-0878
    Keywords: Pinealocytes ; Proteinaceous material ; Ultrastructure ; Mole-rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Résumé Les pinéalocytes de la glande pinéale du Spalax ehrenbergi (animal ayant un appareil visuel atrophié et vivant toujours dans une obscurité complète) examinés au microscope électronique ont été comparés à ceux d'autres Mammifères. Deux populations de pinéalocytes (I and II) ont été observées. Elles diffèrent par la localisation dans la glande, l'aspect du noyau et l'aspect sécrétoire des pinéalocytes. Mitochondries, ribosomes, réticulum endoplasmic granulaire, structures lysosomiales, inclusions lipidiques et grains de glycogène sont présents dans le périkaryon des deux populations de pinéalocytes. De rares grains de sécrétion furent observés dans le corps cellulaire des pinéalocytes I, leur origine golgienne, probable, n'a pu encore être démontrée. De plus, dans le périkaryon de ce type de pinéalocytes des concentrations de ribosomes et de citernes du réticulum endoplasmique granulaire furent toujours observées. La présence d'une accumulation de matériel protéique dans quelques citernes du réticulum endoplasmique granulaire et entre les deux feuillets de l'enveloppe nucléaire est caractéristique des pinéalocytes II. L'origine de ces élements particuliers est discutée.
    Notes: Summary The ultrastructure of pinealocytes of the mole-rat (Spalax ehrenbergi), a blind subterranean mammal living in complete darkness, was examined and compared with pinealocytes of other mammals. Two different populations of pinealocytes (I and II) were observed. They differed in general aspect, in location and especially in their content of cell organelles involved in synthetic processes. Mitochondria, ribosomes, granular endoplasmic reticulum, lysosomes, lipid inclusions and glycogen granules were present in the perikarya of pinealocytes of both populations. In the pinealocyte of population I some granular vesicles were occasionally observed in the cell body. Their presumed origin from the Golgi apparatus could not be clearly demonstrated. In the perikaryon of this pinealocyte, concentrations of ribosomes and of cisternae of the granular endoplasmic reticulum were constantly observed. These concentrations may indicate an intensive synthetic activity. Pinealocytes of population II were characterized by accumulations of proteinaceous material in some cisternae of the granular endoplasmic reticulum and between the two layers of the nuclear membrane. The origin of these peculiar elements is discussed.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-0878
    Keywords: Key words: Secretoneurin ; Pineal gland ; Neuropeptide immunocytochemistry ; Sympathetic nervous system ; Superior cervical ganglion ; Pinealocytes ; Cell culture ; Rat (Wistar) ; Syrian hamster ; Mesocricetus auratus ; Siberian hamster ; Phodopus sungorus (Rodentia)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. The pineal gland of mammals is richly innervated by nerve fibres containing various peptides of central or sympathetic origin. In this study, we have investigated the presence, regulation and effect of secretoneurin (SN), a 33-amino-acid peptide discovered recently in the central and sympathetic nervous systems. The rat pineal gland contains about 34 fmol SN/pineal, although only 20% of the secretoneurin immunoreactivity (SN-IR) is the free peptide. SN-IR is localised in only a few nerve fibres found in the parenchyma of the gland and along the pineal stalk. In the rat pineal, SN-IR shows no midday/midnight differences but is significantly decreased (55%–65%) after superior cervical ganglionectomy or exposure to constant light. These observations suggest that, in the rat pineal, SN-IR originates partly from central areas and partly from the superior cervical ganglia. The pineal of the Syrian hamster contains much more SN-IR: 120 fmol SN-IR/pineal (about 20% being the free peptide). SN-IR is found both in nerve fibres and pineal cells. Some of the fibres run along the pineal stalk, indicating that they are of central origin, although a sympathetic origin cannot be ruled out. Pineal SN-IR is below detectable levels in the Siberian hamster. In cultured rat pinealocytes, SN significantly inhibits serotonin release and, to a lower extent, melatonin release.
    Type of Medium: Electronic Resource
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