ISSN:
1573-7284
Keywords:
Antimicrobial susceptibility
;
Plasmid profile
;
Escherichia coli
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract In an epidemiological study of enteropathogenic Escherichia coli, 102 strains were isolated from patients seen at the University Teaching Hospital in Lagos. The most common serotype encountered was 055 followed by 026. Antimicrobial susceptibility testing and plasmid profiling of the strains were done. All the strains were sensitive to colistin, nalidixic acid, nitrofurantoin, cefotaxime, amikacin, and augmentin. Of the 102 strains, 47 (46%) were resistant to one or more of the following antimicrobial agents: Co-trimoxazole, tetracycline, ampicillin, streptomycin, sulphonamide and a combination of ampicillin with sulbactam. All the strains that were resistant to any antimicrobial agents were also resistant to tetracycline. Seventy-two strains (70.6%) harbored plasmid whose molecular weights ranged from 0.8 to 120 × 106 daltons. The majority. of the plasmid were smaller than 6 × 106; 90% of strains carrying plasmid ranging in size from 2 to 6 × 106 daltons and 50 to 70 × 106 daltons were resistant to one or more antimicrobial agents. Trasformation and conjugation experiment showed that about 57% of the resistant strains carried R plasmid. Plasmld-determined resistance to tetracycline, ampicillin, streptomycin and sulphonamide was found.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00148914
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