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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 419 (1991), S. 566-571 
    ISSN: 1432-2013
    Keywords: Enteric nervous system ; Tachykinin receptors ; Substance P ; Neurokinin A ; Neurokinin B ; Tachykinin analogue
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Responses of gastric myenteric neurones evoked by the mammalian tachykinins substance P (SP), neurokinin A (NKA) and neurokinin B (NKB) were investigated using conventional intracellular recording methods. Application of the tachykinins caused a long lasting depolarization of the membrane potential which was associated with increased spike discharge and augmented excitability of the cells. The responses slowly desensitized. Additionally, cross desensitization occurred between SP, NKA and NKB. Both the NK-1 receptor agonist [Sar9,MetO2 11]SP and the NK-2 receptor agonist [β-Ala8]NKA(4–10) had no effect on the electrical properties of the neurones. Only the NK-3 receptor agonist [MePhe7]NKB mimicked the excitatory response observed during SP, NKA and NKB applications. [MePhe7]NKB-induced desensitization abolished the response to SP, NKA and NKB. However, long lasting applications of [Sar9,MetO2 11]SP or [β-Ala8]NKA(4–10) had no effect on the SP, NKA or NKB responses. The excitatory effect of SP, NKA and NKB remained unchanged during application of the tachykinin analogues [D-Arg1, d-Trp7,9,Leu11]SP and [Tyr5,d-Trp6,8,9,Arg10]NKA(4–10). The results indicate that SP, NKA and NKB act as excitatory neuromodulators within the enteric nervous system of the stomach. The effects of SP, NKA and NKB appeared to be mediated by activation of NK-3 receptors.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 4 (1973), S. 76-81 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Thermal spraying. Thermal spraying in comparison with other coating techniques is characterized by a broad variability of base and spraying materials. After a brief description of actually used equipments some coating properties are summarized. Thermally sprayed special metal will become interesting in near future from commercial and technical point of view. With those metals homogeneous coatings can be produced without porosity.
    Notes: Das thermische Spritzen zeichnet sich gegenüber anderen Verfahren zur Oberflächenbeschichtung durch die Vielfältigkeit der verwendbaren Grund- und Spritzwerkstoffe aus. Neben einer Beschreibung gegenwärtig eingesetzter Geräte wird kurz auf den Schichtaufbau eingegangen. Wirtschaftlich und technisch von besonderem Interesse werden in naher Zukunft thermisch gespritzte Schichten aus Sondermetallen sein, die sich unter Schutzgas porenfrei und homogen erzeugen lassen.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Weinheim [u.a.] : Wiley-Blackwell
    Materials and Corrosion/Werkstoffe und Korrosion 25 (1974), S. 166-171 
    ISSN: 0947-5117
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Structure and properties of special metal coatings applied by thermal sprayingThermal spraying of metals of groups IVa, Va and VI a is difficult because of the fast oxidation of these metals (Ti, Zr, Ta, Nb, W, Mo). It is consequently of vital importance that the atmosphere be oxygen-free, it is that the spray process is carried in an inert atmosphere. In view of the high cost involved in such a system it is necessary to provide for recirculation of an inert gas. The coatings obtained in pure argon are characterized by very high adhesion strength which is due to diffusion phenomena at the base metal/coating interphase. This diffusion takes place at high velocities and the thickness of the diffusion layer depends from the state of perturbation of the superficial zone of the base metal (e. g. perturbation due to sand blasting) and of the perturbation of the atomic structure of the liquid particles at the high temperature. Titanium coatings thus obtained are completely free from inclusions when obrained in argon, while they are severly embrittled when applied under nitrogen. The properties of coatings from all the metals considered (Ti, Zr, Mo, Nb, Ti6A14V) are perfectly comparable to those of the solid metals.
    Notes: Thermisches Spritzen von Metallen der Gruppen 1 Va, Va und VIa ist wegen der leichten Oxidierbarkeit dieser Metalle (Ti, Zr, Ta, Nb, W und Mo) schwierig. Infolgedessen muß die Atmosphäre sauerstoffrei sein, d. h. man muß in inerter Atmosphäre spritzen. Da hierbei die Kosten ziemlich hoch liegen, muß das Schutzgas in Umlauf geführt werden. Die beim Spritzen in reinem Argon erhaltenen Überzüge besitzen sehr hohe Haftfestigkeit, da es zwischen Grundmetall und Überzug zu Diffusionsvorgängen in der Grenzschicht kommt. Diese Diffusion erfolgt mit sehr hoher Geschwindigkeit; die Dicke der Diffusionsschicht ist abhängig vom Störungszustand der Oberflächenzone des Grundmetalls (Störungen hervorgerufen durch Sandstrahlen z. B.) und von der Störung tur der flüssigen Metallteilchen infolge der hohen Temperatur. Die nach den Schutzgas- verfahren erhaltenen Titanüberzüge sind beim Spritzen in Argon vollkommen frei von Ein- flü,ssen, wahrend beim Spritzen unter Stickstoff starke Versprödung auftritt. Bei allen verwendeten Metallen (Ti, Zr, Mo, Nb, Ti6AI4 V) sind die Überzüge mit den massiven Metal- len vergleichbar.
    Additional Material: 15 Ill.
    Type of Medium: Electronic Resource
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