ISSN:
0006-3525
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Complete nmr and CD studies of two cyclic tetrapeptides with disulfide bonds, 1 and 2 bonds have been carried out in different solvents to investigate the formation and stabilization of β-turn structures and to determine the stereochemistry of the disulfide linkage. Both peptides have three-dimensional structures with a type II β-turn, as derived from quantitative nuclear Overhauser effect data. The combined use of CD and nmr indicates that the dihedral angle of the disulfide bridge is different in the two peptides, although the chirality is maintained.
Additional Material:
6 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bip.360310704
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