ISSN:
0009-2940
Keywords:
Allenes, 1,3-diamino- and 1-amino-3-thio-
;
Propene iminium salts
;
Propyne iminium salts
;
MO calculations
;
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Description / Table of Contents:
Propyne Iminium Salts: Ambifunctional reactivity reactivity towards Sulfur and Nitrogen NucleophilesPropyne iminium ions 2a-d have been studied by both ab initio (3-21G//3-21G for 2a) and MNDO calculations (2a-d). It is found that the amino group stabilizes the propargyl cation structure at the expense of the allenyl cation structure. Furthermore, the highest positive charge density is located at the amino-substituted carbon atom. - Reactions of 2-propyne iminium triflates 6a, b with thiols, thiolates, morpholine, lithium morpholide, and phenylhydrazine have been investigated. C-1 attack at 6, expected under kinetically controlled conditions, is observed in a few cases only. In all other cases, products resulting from C-3 attack takes place leading either to 1,3-donorsubstituted allenes (8, 10, 12) in the absence of proton sources or to their C-2-protonated forms (9, 11, 13-15) otherwise.
Notes:
Für die Propiniminium-Ionen 2a-d werden ab-initio- (3-21G//3-21G für 2a) und MNDO-Rechnungen (2a-d) durchgeführt. Danach stabilisiert die Aminogruppe die Propargylkation- eindeutig gegenüber der Allenylkation-Struktur. Die höchste positive Ladungsdichte befindet sich am aminosubstituierten Kohlenstoffatom. - Umsetzungen der 2-Propiniminium-triflate 6a, b mit Thiolen, Thiolaten, Morpholin, Lithium-morpholid und Phenylhydrazin zeigen, daß nur in einigen Fällen unter kinetisch kontrollierten Bedingungen der erwartete C-1-Angriff erfolgt, ansonsten wird C-3-Angriff gefunden. Letzterer führt in Abwesenheit von Protonquellen zu 1,3-donorsubstituierten Allenen (8, 10, 12), andernfalls entstehen deren C-2-protonierte Formen (9, 11, 13-15).
Additional Material:
3 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19891221218
Permalink
