ISSN:
0749-1581
Keywords:
15N NMR spectroscopy
;
Hydrogen bond
;
Proton transfer
;
Pyridines
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The 15N NMR chemical shifts of ten substituted pyridines (B) and their complexes with trifluoroacetic acid (AHB) were measured at the natural abundance level in dichloromethane. The plot of the relative chemical shifts [Δδ(15N)=δ(AHB)—δ(B)] against ΔpKa gives a titration curve which reflects a protometric equilibrium AH…B⇌A-…HB+. These data were used to determine the constants of the overall proton transfer reaction (Kexp). A linear relationship holds between log Kexp and ΔpKa. Δδ(15N) values can be treated as a good hydrogen bond parameter.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260240507
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