ISSN:
1432-2072
Keywords:
Electroencephalography
;
Psychopharmacology
;
Imipramine
;
Amphetamine
;
Physostigmine
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The results of the interaction of imipramine, physostigmine and d/l amphetamine in various intravenously administered dosages were studied on the cortical and subcortical electrical activity of cats. Imipramine was shown to cause a cortical synchronization, hippocampal desynchronization, rise in the threshold of electrocortical arousal and limbic convulsive activity which was potentiated by amphetamine. Imipramine increased the amount of physostigmine, but decreased the amount of amphetamine needed for cortical desynchronization. The possible significance of these findings for the neuropsychopharmacological action of imipramine is briefly discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00404810
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