ISSN:
1573-739X
Keywords:
Anthracyclines
;
Chemistry, physical
;
Qualitative analysis
;
Quantitative analysis
;
Review
;
Stability
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract A review of physicochemical and analytical properties of anthracycline antitumour agents is presented. The following subjects are discussed: protolytic equilibria, partition and partition coefficients, self-association, adsorptive properties, metal complexation, spectroscopy and chromatography. Furthermore, the stability of anthracyclines in solutions, in pharmaceutical preparations and in biological media is discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02086146
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