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  • 1
    ISSN: 1432-2013
    Keywords: RQ ; Insulin ; Glucose ; Lactate ; Pyruvate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary RQ, plasma insulin, blood glucose, lactate and pyruvate were measured in six fit, normal subjects during a series of exercise and rest experiments with and without sucrose ingestion. Subjects exercised on a bicycle ergometer for 50 min of every hour for 6 h at about 47% of the group's average maximal aerobic capacity. In the resting experiments, the subjects sat for 6 h in an armchair. A solution containing 100 g of sucrose was ingested at the beginning of the fourth hour during the sucrose experiments. Ingestion of sucrose caused a significant increase in RQ, plasma insulin, blood glucose, lactate and pyruvate in both exercise and rest experiments. Insulin, lactate and pyruvate concentrations rose higher during rest after sucrose ingestion than during exercise. The time courses of the changes in RQ, insulin, glucose, lactate and pyruvate after sucrose ingestion, suggest that glucose entering the cell during rest is immediately oxidized, while during work there is some delay in the oxidation of glucose.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2013
    Keywords: RQ ; C14O2 ; Lactate ; Pyruvate ; Carbohydrate Utilization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Four well-trained male subjects worked for periods of 6 h on bicycle ergometers at work loads requiring about 47% of their maximal aerobic capacity. In one series of studies they received only water; in a second series they received 100 g of sucrose containing 100 μc U-C14-labelled sucrose at the beginning of the fourth hour of work. In a third series of experiments, the same subjects received 100 g of non-labelled sucrose at the beginning of the fourth hour. During the experiment without U-C14-labelled sucrose, blood samples were withdrawn and analysed for glucose, lactate and pyruvate content. Data from C14O2 recovery in expired air showed a good correlation with the amount of carbohydrate oxidized during the sucrose experiment. Peak values for the respiratory exchange ratio showed the same time response as those observed for the C14O2 in the expired air. It is concluded that the observed rise in RQ after sucrose ingestion, under the conditions studied, is of metabolic origin, resulting from a complete conversion of pyruvate to CO2.
    Type of Medium: Electronic Resource
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