ISSN:
1432-0878
Keywords:
Adrenal vasculature
;
Portal system
;
Microspheres
;
Rat
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary The intra-glandular vascular arrangement in the adrenal has been studied using non-radioactive microspheres injected by three different routes: in-vivo injection into the left ventricle under pentobarbital anesthesia, postmortem orthograde, and postmortem retrograde injection. The doses of microspheres were 105 (average size 24.7 μm), 106 (15.8 μm) and 107 (9.9 μm). The entrapment rate of microspheres by the medulla as compared with the whole gland was measured in the serially sectioned tissue (section thickness 60 μm). The entrapment rates of 25-μm microspheres differed between the orthograde and retrograde injections, while the entrapment rates for 15-μm microspheres were essentially similar irrespective of the route of injection. Our results support the conclusion from previous microangiographic studies that the adrenal cortex and medulla are supplied by different arteries but have a common venous outflow, and that direct communication between cortical and medullary sinusoids is not likely. The medullary blood flow per gram tissue weight is estimated to be larger than cortical blood flow.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00222335
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