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  • 1
    ISSN: 1432-1106
    Keywords: Synapse ; Granular vesicles ; Noradrenaline ; Nialamid ; Ventromedial hypothalamic nucleus ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The fine structure of ventromedial hypothalamic nucleus was studied in the rat with the electron microscope under circumstances of elevated brain monoamine level following treatment with a monoamine oxidase inhibitor Nialamid. The number of granular vesicles (size in diameter 450–1100 Å) in synaptic terminals increased after Nialamid treatment significantly, while their size did not change; the number of agranular vesicles remained unchanged. The time courses of the increase of granular vesicles and elevation of brain noradrenaline content were approximately parallel. It is inferred that the granular vesicles of size 450 to 1100 Å may possibly be the storage sites of noradrenaline.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 22 (1975), S. 525-540 
    ISSN: 1432-1106
    Keywords: Supraoptic nucleus ; Quantitative electron microscopy ; Afferent fiber connections ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A quantitative electron microscopic study of synaptic terminal degeneration was performed in the supraoptic nucleus (NSO) after a variety of major transections or ablations, destroying or interrupting in different combinations the afferent pathways known from earlier and own light microscopic degeneration studies. Solutions of a set of equations, expressing the percentage degenerations in synaptic profiles after different combinations in which the several pathways are interrupted by the various interferences, enabled the authors to give the following percentage numbers for afferent synapses from different sources. 32.7% of supraoptic afferents originate from the brain stem probably representing the monoaminergic innervation of this nucleus. The medial basal hypothalamus (21.0%), amygdala (13.5%), septum (13.5%), hippocampus (8.5%) and olfactory tubercle and further rostral cortical region (17.0%) are the other main sites of origin of supraoptic nucleus afferents. There are no supraoptic afferents from the optic nerve, superior cervical ganglion or fimbria hippocampi.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 241 (1985), S. 445-451 
    ISSN: 1432-0878
    Keywords: Bed nucleus of the stria terminalis (NIST) ; Blood supply ; Double-ink perfusion ; Arteries ; Veins ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The topographical distribution of the blood vessels in the bed nucleus of the stria terminalis (NIST) has been mapped in rats. Arteries and veins were visualized in red and blue by using a double-ink perfusion technique. Arteries supplying the NIST arise from the anterior cerebral artery directly or through the anterior communicating and interhemispheric arteries. Only a few, dorsal branches derive from the medial cerebral artery through thalamostriatal arteries. According to their terminal branches, NIST arteries can be divided into five groups: medial, ventral, lateral, septal and dorsal, which have only a relatively small overlap in their territories. About 90% of veins from the NIST drain into the major basal veins. Medial branches run into the perioptic and interhemispheric veins, while the ventral branches and the large lateral vein drain directly into the anterior cerebral vein. A small proportion of NIST veins run dorsalward into the vena cerebri magna via thalamostriatal veins.
    Type of Medium: Electronic Resource
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