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Digitale Medien

An improved method for estimating sequence divergence of DNA using restriction endonuclease mappings (1981)

Kaplan, N. ; Risko, K.

Springer

Journal of molecular evolution 17 (1981), S. 156-162

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Details

ISSN: 1432-1432

Schlagwort(e): Evolution, Poisson process ; Restriction endonuclease mappings ; Mitochondrial DNA ; Nucleotide diversity

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie

Notizen: Summary The method proposed by Kaplan and Langley for estimating the extent of sequence divergence between related DNA's using restriction endonuclease maps is modified so that the estimates are easier to compute. In the two-species case, these modifications lead via a maximum likelihood approach to an estimate which is closely related to one recently suggested by Nei and Li (1979) and Gotoh et al. (1979). Simulation studies show that the modified estimates are comparable to those of Kaplan and Langley, providing that there is sufficient homology in the DNA segments of the related species. The M-species case, M ⩾ 3, is also discussed.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01733909

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