ISSN:
1432-1432
Keywords:
Evolution, Poisson process
;
Restriction endonuclease mappings
;
Mitochondrial DNA
;
Nucleotide diversity
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary The method proposed by Kaplan and Langley for estimating the extent of sequence divergence between related DNA's using restriction endonuclease maps is modified so that the estimates are easier to compute. In the two-species case, these modifications lead via a maximum likelihood approach to an estimate which is closely related to one recently suggested by Nei and Li (1979) and Gotoh et al. (1979). Simulation studies show that the modified estimates are comparable to those of Kaplan and Langley, providing that there is sufficient homology in the DNA segments of the related species. The M-species case, M ⩾ 3, is also discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01733909
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