ISSN:
1573-5117
Keywords:
Secondary metabolites
;
oxylipins
;
eicosanoids
;
algae
;
seaweeds
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract Our previous research has shown that many red algae metabolize polyunsaturated fatty acids to oxidized products resembling the eicosanoid hormones from mammals. We have extended these studies to members of the Phaeophyceae and Chlorophyta and find they also possess similar biosynthetic pathways. From several we have identified novel prostaglandin-like substances. Studies of the molecular mechanisms by which some of these marine oxylipins are formed have revealed that novel oxidative reactions are utilized. Understanding of these biosynthetic pathways in detail has allowed their utilization to produce research biochemicals of high value, such as 12S-hydroperoxyeicosatetraenoic acid (12S-HPETE). Because of their biological properties, seaweed-derived oxylipins have potential utility as pharmaceuticals and research biochemicals.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00049085
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