ISSN:
1432-1106
Keywords:
Septo-hippocampal projection
;
Fimbria-fornix transection
;
Hippocampal commissural projection
;
Anterograde tracing
;
Rat
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract This study describes an approach for disconnecting the septal region from the hippocampus by fimbria-fornix lesions while sparing the commissural projections. After a frontal cut through the rostral fornix, commissural fibres were labelled with the anterograde tracer Phaseolus vulgaris leucoagglutinin. The commissural fibre bundle located in the posterior-basal fornix (ventral hippocampal commissure) remained unaffected by the rostral fornix transection, whereas the absence of septal fibres in the hippocampus could be verified using AChE histochemistry. Thus, using this approach, selective studies of the septo-hippocampal projection can be performed while leaving the overwhelming portion of the commissural fibre system intact.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00242010
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