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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 310 (1969), S. 109-115 
    ISSN: 1432-2013
    Keywords: Effective Filtration Pressure ; Single Nephron Filtration Rate ; Einzelnephronfiltrat ; Effektiver Filtrationsdruck
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Mit Hilfe der Mikropunktionstechnik wurde die Filtrationsrate einzelner nahe der Nierenoberfläche gelegener Glomeruli gemessen. Die tubuläre Flüssigkeit wurde dabei einmal durch kontrollierten Sog an der Punktionscapillare, zum anderen entgegen dem proximalen Freiflußdruck quantitativ gesammelt. Die ermittelten Einzelfiltrate waren 35,2±14,3 (SD) bzw. 18,3±5,7 (SD) mμl/min. Dieser Unterschied wird auf die Erhöhung des effektiven Filtrationsdruckes durch das Absaugen der tubulären Flüssigkeit zurückgeführt.
    Notes: Summary Single nephron filtration rate was measured in superficial tubules of the rat kidney. We used two different methods for sampling tubular fluid: 1. controlled suction 2. sampling against the predetermined intratubular free-flow pressure. The measured filtration rates were 35.2±14.3 (SD) and 18.3±5.7 (SD) mμl/min, respectively. We interpret this difference as being due to the increase in effective filtration pressure during sucking of tubular fluid.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2013
    Keywords: Effective Filtration Pressure ; Single Nephron Filtration Rate ; Permeability of Glomerular Capillary Membranes ; Effektiver Filtrationsdruck ; Einzelnephronfiltrat ; Permeabilität der glomerulären Capillarmembran
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Single nephron filtration rate (GFRs) and effective glomerular filtration pressure (EFP) measured as the difference between intratubular stop-flow (SFP) and free-flow pressures (FFP), were determined in control rats and following saline infusion or hemorrhage. Infusion of isotonic or 4% NaCl increased EFP and GFRs without significantly affecting TF/P inulin. These findings could not be related to changes in arterial blood pressure. Controlled bleeding produced a marked decrease in EFP and in GFRs, again without significant change in TF/P-inulin. In both infusion and hemorrhage the change in GFRs was disproportionately greater than the change in EFP. Analysis of the components of the filtration process suggests that elevation of EFP is attended by an increase in permeability of the filtering membrane. This sensitive dependence of GFRs upon EFP, combined with a demonstrated constancy of total kidney GFR (GFRT) over a wide range of urine concentrations and flow rates, connotes a close regulation of EFP in this experimental animal.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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