ISSN:
1432-2013
Keywords:
Skinned fibres
;
Exercise
;
Swimming
;
Fibre types
;
Muscle contraction
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Single fibres were isolated from the extensor digitorum longus (EDL) and the soleus (SOL) muscles of the hindlimb from young male Wistar rats which had undergone a 10-week programme of endurance swimming from the age of 2 weeks. Fibres were mechanically skinned and activated with Ca2+- and Sr2+ -buffered solutions. Muscle fibres were classified by means of well-defined criteria concerning various aspects of their contractile behaviour. Most fibres could be allocated into specific groups; however, a significant proportion (13% of the sampled population) did not fit these rigid classifications but displayed contractile activation characteristics common to more than one fibre type. In these cases models which used a combination of both fast- and slow-twitch contractile and regulatory properties were used to characterise the activation behaviour of fibres. It is proposed that the exercise, initiated at a young age, induced changes in the contractile characteristics of the single fibres by modifying protein isoforms of the contractile apparatus.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00370466
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