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  • 1
    Electronic Resource
    Electronic Resource
    Effects of loprazolam and of triazolam on sleep and overnight urinary cortisol (1984)
    Springer
    Psychopharmacology 82 (1984), S. 389-394 
    Details
    ISSN: 1432-2072
    Keywords: Sleep ; Loprazolam ; Triazolam ; Tolerance ; Rebound ; Cortisol ; Noradrenaline
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Nine poor sleepers of mean age 61 years were studied while they took loprazolam 0.5 mg, loprazolam 1 mg and triazolam 0.5 mg for 3-week periods. Loprazolam 1 mg and triazolam 0.5 mg increased sleep duration, but there was some tolerance to both, particularly triazolam, by the 3rd week. Withdrawal of either drug led to sleep significantly shorter than baseline. This rebound effect was significant greater after withdrawing triazolam. After withdrawing loprazolam 1 mg, the rebound was maximal on the 3rd night and after withdrawing triazolam it was maximal and severe on the 1st night. In the third week of use neither drug was associated with late-night wakefulness. Total overnight urinary cortisol was lower during drug intake and there were significant withdrawal rebounds to above baseline levels, immediately so after triazolam.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00427692
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  • 2
    Electronic Resource
    Electronic Resource
    Improved physical fitness failed to alter the EEG patterns of sleep in young women (1989)
    Springer
    European journal of applied physiology 59 (1989), S. 123-127 
    Details
    ISSN: 1439-6327
    Keywords: Fitness ; Exercise ; Sleep ; Training
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We investigated the effect of a 12-week physical training programme on the sleep of nine unfit women. Data were collected at 0, 4, 8 and 12 weeks of the training programme. Changes in fitness were assessed by changes in maximal oxygen consumption ( $$\dot V_{O_{2\max } } $$ ) and onset of blood lactate turn point (LTP). Lean body mass (LBM) was calculated from total body potassium measurements. The all-night sleep recordings were made following days during which the subjects carried out their normal daily routines and did no extra exercise. Although cardiorespiratory fitness improved significantly as indicated by an increase in both $$\dot V_{O_{2\max } } $$ and LTP, there was no change in LBM. The improvement in cardiorespiratory fitness did not result in any changes in the sleep parameters measured. Other workers have reported an improvement in sleep quality in eight army recruits during their basic training. The male recruits showed improved cardiorespiratory fitness and an increase in muscle bulk. These results suggest that increased fitness only facilitates sleep when there is an associated increase in LBM. Alternatively it may be that the response of sleep to improved fitness is sex-linked.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02396589
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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