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  • 1
    Electronic Resource
    Electronic Resource
    Spezifikation und Prototyping graphbasierter Systeme (1996)
    Springer
    Informatik, Forschung und Entwicklung 11 (1996), S. 191-202 
    Details
    ISSN: 0949-2925
    Keywords: Schlüsselwörter: Graphersetzungssysteme ; Prototyping ; Spezifikationssprachen ; Key words: Graph rewriting systems ; prototyping ; specification languages
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Abstract. The specification language PROGRES has been developed for the systematic design and realization of graph structures and operations on them. It is statically typed, its static and dynamic semantics is formally defined. It offers both, rule based and imperative language constructs and supports modeling of complex structures in interactive systems and by the means of PROgrammed Graph REwriting Systems. We want to show the suitability of the PROGRES language and environment for the operational specification and generation of prototypes for this kind of systems. We focus on the tightly integrated tools, which allow editing, analyzing, and executing specifications in an intertwined way. Features of the generated prototypes are extendibility, data persistence, recovery, and multi user support.
    Notes: Zusammenfassung. Zum systematischen Entwurf und zur Realisierung von Graphstrukturen und ihrer Zugriffsoperationen wurde die Spezifikationssprache PROGRES entwickelt. Sie unterstützt das Modellieren komplex strukturierter Sachverhalte, wie sie beim Bau interaktiver Systeme auftreten. Sie erlaubt die gemischt regelorientierte bzw. imperative Formulierung entsprechender Zugriffsoperationen mit Hilfe PROgrammierter GRaph-Ersetzungs-Systeme, besitzt ein statisches Typsystem, eine vollständige formale Definition ihrer statischen und dynamischen Semantik und ist sowohl interpretativ als auch kompilativ ausführbar. Hier soll die Eignung der Sprache PROGRES und ihrer Entwicklungsumgebung zur operationalen Spezifikation entsprechender Systeme und zur Generierung von Prototypen gezeigt werden. Dabei legen wir ein besonderes Gewicht auf die Unterstützung durch die enge Integration ihrer Werkzeuge, die das verschränkte Editieren, Analysieren und Ausführen gestatten. Bei den generierten Prototypen stehen leichte Erweiterbarkeit, Persistenz der Daten, Recovery und Mehrbenutzerfähigkeit im Vordergrund.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004500050061
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Calcium acetate versus calcium carbonate as oral phosphate binder in pediatric and adolescent hemodialysis patients (1996)
    Springer
    Pediatric nephrology 10 (1996), S. 625-630 
    Details
    ISSN: 1432-198X
    Keywords: Key words: Calcium acetate   ;   Calcium carbonate   ;   Pediatric hemodialysis   ;   Hypercalcemia   ;   Phosphate binder   ;   Parathyroid hormone   ;   Hyperparathyroidism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Calcium carbonate is widely used as an oral phosphorus binder to control hyperphosphatemia in children on maintenance hemodialysis. Intestinal calcium absorption may induce hypercalcemia, particularly if calcitriol is given simultaneously. In adults, calcium acetate binds phosphorus more effectively than calcium carbonate, while reducing the frequency of hypercalcemic events. We therefore compared calcium acetate with calcium carbonate in nine pediatric patients on long-term maintenance hemodialysis. Following a 1-week withdrawal of phosphorus binders, calcium carbonate was administered for 7 weeks; after a second withdrawal, calcium acetate was given for another 7 weeks. All patients received calcitriol regularly. Both agents lowered the serum phosphorus concentration significantly (calcium carbonate 5.7±1.4 vs. 7.7±2.1 mg/dl, P〈0.005; calcium acetate 5.8±1.4 vs. 7.8±2.0 mg/dl, P〈0.005). Significantly less elementary calcium was ingested with calcium acetate than with calcium carbonate: 750 (375 – 1,500) vs. 1,200 (0 – 3,000) mg calcium/day, P〈0.0001. With calcium carbonate serum calcium increased significantly. The number of episodes of hyperphosphatemia or hypercalcemia did not differ between treatments. Intact plasma parathyroid hormone (PTH) decreased significantly with both phosphate binders, and serum 25-hydroxyvitamin D3 increased. There was a close relationship between serum phosphorus and PTH in prepubertal but not in pubertal patients. We conclude that hyperphosphatemia can be controlled effectively by both calcium acetate and calcium carbonate in pediatric hemodialysis patients. The oral load of elementary calcium is reduced significantly by binding phosphorus with calcium acetate instead of calcium carbonate; nevertheless, hypercalcemic episodes remain equally frequent with both phosphate binders.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004670050175
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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