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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Documenta ophthalmologica 29 (1971), S. 261-287 
    ISSN: 1573-2622
    Keywords: Sclera ; Graft ; Staphyloma ; Surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Fifteen case histories illustrate a wide variety of indications and techniques for scleral surgery. No significant technical difficulties occurred during any of these procedures. Few post-operative complications ensued, and none caused serious consequences. In an attempt to arrest possibly progressive staphylomas, grafts can be performed on prophylactic bases. Such prophylactic surgical therapy may be useful in carefully selected circumstances, especially when trauma is likely to recur, or when elevated intraocular pressure is likely to develop.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International ophthalmology 17 (1993), S. 19-22 
    ISSN: 1573-2630
    Keywords: retinal apposition ; water movement ; rabbit ; composite membranes ; barriers ; vitreous ; retina ; retinal pigment epithelium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Water movement from the vitreous to the choroid would tend to maintain retinal apposition, if the retina were less permeable than the retinal pigment epithelium (RPE). We used a rabbit model, to test the relative permeability of retina and RPE to tritiated water. The retina was found less permeable than the RPE. This result suggests the presence of a hydrostatic pressure gradient across the retina which could enhance apposition of retina to the RPE.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International ophthalmology 9 (1986), S. 5-9 
    ISSN: 1573-2630
    Keywords: drug delivery ; intravitreal cannula ; monkey ; rabbit
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An intravitreal cannula for chronic drug delivery was implanted in the eyes of two rabbits and one monkey. The rabbits were followed up for three years after surgery and the monkey was followed up for two and one-half years. Clinical observations did not reveal any adverse effects from the cannula implantation. Patency of the cannula was demonstrated by using sodium fluorescein. Histopathological studies with light and electron microscopy revealed the scar tissue around the cannula to be minimal and localized to the wound site. The optic nerve and the retina and choroid at the posterior pole did not show any abnormalities. These results suggest that this system can be used for repeated or continuous drug delivery to the vitreous over a long period of time in experimental models.
    Type of Medium: Electronic Resource
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