ISSN:
1432-1041
Keywords:
Chlorpropamide
;
T.L.C. assay
;
bioavailability in man
;
formulation differences
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary A specific TLC assay procedure has been used to compare the bioavailability of three brands of chlorpropamide, Diabetasi, Diabinese, and Prodiaben. Serum concentrations of drug were determined at various times after administration of single oral doses to normal volunteers in a crossover study. Prodiaben gave significantly lower serum levels than the other two brands during the first 24 h after dosing.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00614389
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