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  • 1
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Gamete Research 7 (1983), S. 347-350 
    ISSN: 0148-7280
    Keywords: Taurine-related compounds ; taurine antagonists ; taurine uptake inhibitors ; fertilization in vitro ; hamster ; spermatozoa ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: Several taurine-related compounds, taurine antagonists and taurine uptake inhibitors were tested for their effect on hamster sperm motility in vitro. Hypotaurine was approximately three times more effective than taurine. N-methyltaurine and taurocyamine were less effective. Inactive taurine-related compounds were not effective blockers of taurine's spermtimulating activity. However, 1-(4-nitrophenyl)-2-dimethylaminomethyl-l-propenone, a taurine uptake inhibitor, completely suppressed sperm motility at a molar concentration equal to, or less than, that of the taurine added to the incubation medium and also suppressed the motility-sustaining action of the cumulus oophorus.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0148-7280
    Keywords: assisted fertilization ; t-locus mice ; in vitro fertilization ; infertility ; mouse ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: Failure of epididymal spermatozoa from T/t mutant mice, but not from t/t individuals, to fertilize oocytes in vitro was partially overcome by opening a small aperture in the zona pellucida with acidified Tyrode's solution to permit direct access of the spermatozoon to the vitellus. This study provides a model system to evaluate requirements for successful zona drilling in the treatment of human infertility and further insights into the effects of the t complex on sperm fertility.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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