ISSN:
1432-1432
Keywords:
3-Isoisoguanosine 5′-phosphate
;
3-Isoxanthosine 5′-phosphate
;
Template-directed synthesis
;
Phosphoroimidazolides
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary We have studied the oligomerization reactions of the 2-methylimidazolide derivatives of 3-isoisoguanosine 5′-phosphate (2) and 3-isoxanthosine 5′-phosphate (5) in the presence of a variety of homopolynucleotide templates. In no case did we observe a substantial template-facilitated production of long oligomers. Polyuridylic acid directed the synthesis of low molecular-weight products from both monomers. Polycytidylic acid, polyadenylic acid, polyinosinic acid, and polyguanylic acid were ineffective as templates in the systems that we investigated.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02102646
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