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Tetralogy of Fallot in three siblings: a familial study and review of the literature (1992)

Pacileo, G. ; Musewe, N. N. ; Calabrò, R.

Springer

European journal of pediatrics 151 (1992), S. 726-727

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ISSN: 1432-1076

Keywords: Tetralogy of Fallot ; Familial study ; Multifactorial inheritance

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract We report a family in which three out of four siblings had tetralogy of Fallot (TOF). The family history showed TOF in the daughter of a maternal cousin, while no other congenital heart diseases were discovered. Although no teratogenic environmental agent was discovered, the absence of parental consanguinity and the presence of another affected relative suggest multifactorial inheritance. Autosomal recessive inheritance cannot be ruled out.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01959076

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